货号:10007431-1 mg | 规格:1 mg | 目录价:¥6118 |
货号:10007431-100 µg | 规格:100 µg | 目录价:¥798 |
货号:10007431-500 µg | 规格:500 µg | 目录价:¥3486 |
产品详情
产品名称:
N-Arachidonoyl Dopamine-d8
别名:
NADA-d8
产品描述:
N-Arachidonoyl dopamine-d8 is intended for use as an internal standard for the quantification of N-arachidonoyl dopamine (Item No. 90057) by GC- or LC-MS. Several different arachidonoyl amino acids, including NADA, have been isolated and characterized from bovine brain.{9589} NADA is the amide of the neurotransmitter dopamine and arachidonic acid. NADA is a CB1-selective cannabinoid agonist, inducing the typical tetrad of hypothermia, analgesia, catalepsy, and hypomotility in rats which exceeds that of anandamide (AEA).{9213} NADA is a full agonist at the vanilloid receptor 1, but is inactive on the dopaminergic D1 and D2 receptors. NADA is also a potent inhibitor (IC50 = 0.25 µM) of the proliferation of MCF-7 breast carcinoma cells. Recent reports of NADA’s endothelium-dependent vasodilation indicate that some of its cannabinergic activities antagonized by SR141716A may be non-CB1/CB2 dependent.{11224}
保存温度:
-20
运输温度:
-20
预期分子量:
447.6
产品形式:
A solution in ethanol
有效期:
730
纯度:
≥99% deuterated forms (d1-d8)
CAS号:
1159908-42-5
分子式:
C28H33D8NO3
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