N-Arachidonoyl-L-Serine-d8-脂质-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳九游会j9网站首页有限公司

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N-Arachidonoyl-L-Serine-d8

品牌：Cayman

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说明书

折扣/货期

货号：10007428-1 mg	规格：1 mg	目录价：￥5194
货号：10007428-100 µg	规格：100 µg	目录价：￥672
货号：10007428-500 µg	规格：500 µg	目录价：￥2940

产品详情

产品名称:

N-Arachidonoyl-L-Serine-d8

别名:

ARA-S-d8

产品描述:

N-Arachidonoyl-L-serine-d8 (ARA-S-d8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of ARA-S (Item No. 10005455) by GC- or LC-mass spectrometry. Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature.{9213} ARA-S is one such recently isolated endocannabinoid with an unusual activity profile. ARA-S does not bind to CB1 and CB2 receptors or vanilloid receptor 1. Like cannabidiol (Item No. 90080), ARA-S (5 mg/kg) antagonizes the hypotensive effects of a 10 mg/kg IV bolus of abnormal cannabidiol (Abn-CBD, CAY10429 Item No. 10004259) in an anesthetized rat blood pressure model.{11984} However, similar to Abn-CBD, ARA-S relaxes isolated rat mesenteric arteries and abdominal aorta, as well as increases phosphorylation of Akt and MAPK in HUVEC.{14066} The precise mechanisms of action by ARA-S and Abn-DBD in various vascular preparations appears to be different and requires further investigation.

保存温度:

-20

运输温度:

-20

预期分子量:

399.6

产品形式:

A solution in ethanol

有效期:

365

纯度:

≥99% deuterated forms (d1-d8)