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TDO (Anopheles gambiae) (rec.) (His)
品牌：Adipogen
货号：AG-40T-0101-C050 规格：50 ug 目录价：￥4680
产品详情
产品名称:
TDO (Anopheles gambiae) (rec.) (His)
别名:
TPH2; TRPO; Tryptophan 2,3-dioxygenase; Tryptophan Oxygenase; Tryptophan Pyrrolase; Tryptophanase
产品描述:
Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin; in mosquitoes, the kynurenine pathway is essential for eye pigmentation. Conceivably, the tryptophan-using pathways should be regulated in a coordinated manner in mosquitoes as well as in other species and TDO activation/inactivation processes could play an essential role in these phenomena.
宿主来源:
Synthetic.
产品浓度:
0.5mg/ml (Lot specific)
保存温度:
-80°C
运输温度:
DRY ICE
预期分子量:
~47.9kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10% glycerol.
有效期:
Stable for at least 6 months after receipt when stored at -80°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Specific activity towards L-Trp: 87.0µmol/hr per mg. TDO catalyzes the oxidative opening of the L-tryptophan indole moiety to yield N-formylkynurenine (NFK).
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