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    NMNAT3 (human) (rec.) (His) (highly active)
    品牌：Adipogen
    货号：AG-40T-0093-C010 规格：10 ug 目录价：￥2520
    货号：AG-40T-0093-C050 规格：50 ug 目录价：￥5880
    产品详情
    产品名称:
    NMNAT3 (human) (rec.) (His) (highly active)
    别名:
    Nicotinamide Mononucleotide Adenylyltransferase 3; NMN Adenylyltransferase 3; NaMN Adenylyltransferase 3; EC 2.7.7.18; EC 2.7.7.1
    产品描述:
    Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.
    宿主来源:
    E. coli
    产品浓度:
    1mg/ml
    保存温度:
    -20°C
    运输温度:
    BLUE ICE
    预期分子量:
    ~27kDa (monomer)
    产品形式:
    liquid
    存储溶液:
    Liquid. In 50mM TRIS-HCl, pH 8.0, containing 300mM sodium chloride, 1mM DTT and 10% glycerol.
    有效期:
    Working aliquots are stable for up to 3 months when stored at -20°C.
    产地:
    瑞士
    纯度:
    >95% (SDS-PAGE)
    生物活性:
    >2U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1µmol of NAD+ per min.
    内毒素水平:
    N/A
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