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折扣/货期| 货号：AG-44B-0006-KI01 | 规格：1 Set | 目录价：￥5520 |
产品详情
产品名称:
IDO1 (human) Enzyme+Inhibitor Set
别名:
Indoleamine 2,3-dioxygenase; INDO; IDO
产品描述:
IDO1 is a heme-containing enzyme that catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway, causing depletion of tryptophan which can lead to halted growth of microbes as well as T cells. IDO1 is an immune checkpoint protein, that plays a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation and antioxidant activity. The IDO1 (human) Enzyme+Inhibitor Set contains the active enzyme IDO1 (human) (rec.) (His) (AG-40B-0161), compound MMG-0358 (AG-CR1-3630), a very potent and specific inhibitor of IDO1, and protocols that can be used for IDO1 enzyme activity and IDO1 inhibition experiments. Both components can be used in vitro: • For cell culture to study the effect of hIDO1 in a cellular system.• For screening assay to search for new inhibitors of hIDO1.
保存温度:
-20°C
运输温度:
DRY ICE
有效期:
Stable for at least 6 months after receipt when stored at -20°C.
产地:
瑞士
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