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折扣/货期| 货号：15-1024 | 规格：100 Reactions | 目录价：￥4860 |
产品详情
产品名称:
SMARCA5 Chromatin Remodeling Enzyme
产品描述:
Full length recombinant human SMARCA5 Remodeling Enzyme. SMARCA5 is a core ATPase subunit of the ATP-dependent chromatin remodeling ISWI complexes that regulate nucleosome spacing to control DNA accessibility [1,2]. SMARCA5 containing complexes exhibit substrate preference and distinct remodeling directionalities with different regulatory subunits [3]. Mis-regulation of SMARCA5 is linked with multiple human cancers including leukemia, breast, lung, and gastric cancers [4]. SMARCA5 can be used in conjunction with EpiDyne®-FRET Remodeling Assay Substrate (EpiCypher 16-4201) in HTS-compatible drug discovery studies.
宿主来源:
Human
表达系统:
SF9 cells
保存温度:
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.
运输温度:
Dry ice.
产品形式:
SMARCA5 at 0.038 mg/mL in 32.5 µL of 25 mM HEPES pH 7.6, 0.1 mM EDTA, 10% glycerol, 200 mM NaCl, 1 mM DTT, 0.4 mM PMSF, 1 mM benzamidine, 0.02% NP-40, 0.4 mg/mL insulin.
产地:
美国
生产商:
EpiCypher
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