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折扣/货期| 货号：15-1014 | 规格：100 Reactions | 目录价：￥6900 |
产品详情
产品名称:
SMARCA4 Chromatin Remodeling Enzyme
产品描述:
Full length recombinant human SMARCA4 Chromatin Remodeling Enzyme. SMARCA4 is a core ATPase subunit of the ATP-dependent chromatin remodeling complex SWI/SNF that mobilizes nucleosomes and plays key roles in gene transcription regulation, development, genome replication and repair [1,2]. Aberrant activity of SWI/SNF subunits is linked with more than 20% of human cancers and multiple developmental disorders, making SMARCA4 an emerging candidate therapeutic target [3,4]. SMARCA4 can be used in conjunction with EpiDyne®-FRET Remodeling Assay Substrate (EpiCypher 16-4201) in HTS-compatible drug discovery studies.
宿主来源:
Human
表达系统:
SF9 cells
保存温度:
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.
运输温度:
Dry ice.
产品形式:
SMARCA4 at 0.080 mg/mL in 10.6 µL of 25 mM HEPES pH 7.6, 0.1 mM EDTA, 10% glycerol, 350 mM NaCl, 1 mM DTT, 0.4 mM PMSF, 1 mM benzamidine, 0.02% NP-40, 0.4 mg/mL insulin.
产地:
美国
生产商:
EpiCypher
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