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R-1 Methanandamide Phosphate

品牌：Cayman

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说明书

折扣/货期

货号：10004281-1 mg	规格：1 mg	目录价：￥952
货号：10004281-10 mg	规格：10 mg	目录价：￥6748
货号：10004281-5 mg	规格：5 mg	目录价：￥4228

产品详情

产品名称:

R-1 Methanandamide Phosphate

别名:

(R)-(+)-Arachidonyl-1'-Hydroxy-2'-Propylamide Phosphate|R-1MAP

产品描述:

Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as Δ9-THC.{1134,2713} Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (2-AG).{2713} The phosphate ester of R-1 methanandamide, R-1MAP, has been tested as a water soluble prodrug analog of AEA.{11520} The activity of R-1MAP was essentially equivalent to that of AEA in the growth inhibition of C6 glioma cells. However, when tested for inhibition of AEA binding to isolated rat brain CB1 receptors, arachidonoyl ethanolamide phosphate (AEA-P) is about 5-fold less potent as an agonist with a Ki of about 200 nM.{9580} The phosphate esters of AEA and its analogs are also structural variants of lysophosphatidic acid (LPA). However, the effects of R-1MAP on the various LPA receptors have not been tested.

保存温度:

-20

运输温度:

-20

预期分子量:

441.5

产品形式:

A solution in ethanol

有效期:

365

纯度:

≥98%