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PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)
货号:10007764-1 mg 规格:1 mg 目录价:¥6398
货号:10007764-100 µg 规格:100 µg 目录价:¥840
货号:10007764-500 µg 规格:500 µg 目录价:¥3626
产品详情
产品名称:
PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt)
别名:
DOPI-3,4,5-P3|Phosphatidylinositol-3,4,5-trisphosphate|PI(3,4,5)P3 (8:0/8:0)|PIP3[3',4',5'](8:0/8:0)
产品描述:
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. The short fatty acid chains of this analog give it different physical properties including high solubility in aqueous media compared to naturally occurring PtdIns-(3,4,5)-P3. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Phosphorylation of PtdIns-(4,5)-P2 by phosphoinositide (PI)-3-kinase initiates an intricate signalling cascade at the fore front of scientific research.{12235}
保存温度:
-20
运输温度:
-20
预期分子量:
914.5
产品形式:
A lyophilized powder
有效期:
1825
纯度:
≥98%
分子式:
C25H46O22P4 • 4Na
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