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Palmitic Acid
品牌:Cayman
货号:10006627-10 g 规格:10 g 目录价:¥448
货号:10006627-100 g 规格:100 g 目录价:¥1708
货号:10006627-25 g 规格:25 g 目录价:¥784
货号:10006627-50 g 规格:50 g 目录价:¥1092
产品详情
产品名称:
Palmitic Acid
别名:
C16:0|Cetylic Acid|FA 16:0|Hexadecanoic Acid|NSC 5030
产品描述:
Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.{45765,1935} Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellular proteins, promotes protein-vesicle interactions, and regulates various G protein-coupled receptor functions.{45765} Palmitic acid (200 µM) increases NF-ĸB p65 levels, matrix metalloproteinase-9 (MMP-9) activity, and production of reactive oxygen species (ROS) in AsPC-1 pancreatic cancer cells, as well as increases migration of AsPC-1 cells.{45766} It increases COX-2 levels in RAW 264.7 cells and increases LPS-induced IL-1β levels and caspase-1 activity in isolated mouse peritoneal macrophages.{10646,45767} Dietary administration of palmitic acid (2.2% w/w for 12 weeks) increases mouse hippocampal β-secretase 1 (BACE1) activity and amyloid β (1-42) (Aβ42; Item No. 20574) levels.{45768} It also induces systolic contractile dysfunction in isolated mouse hearts.{45769} Red blood cell palmitic acid levels are increased in patients with metabolic syndrome compared to patients without metabolic syndrome and are also increased in the plasma of patients with type 2 diabetes compared to individuals without diabetes.{45771,45772}
保存温度:
-20
运输温度:
-20
预期分子量:
256.4
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
来源:
Plant/Palm
CAS号:
57-10-3
分子式:
C16H32O2
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