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N-Nervonoyl Taurine
品牌:Cayman
货号:10007287-1 mg 规格:1 mg 目录价:¥1176
货号:10007287-10 mg 规格:10 mg 目录价:¥9114
货号:10007287-5 mg 规格:5 mg 目录价:¥5166
产品详情
产品名称:
N-Nervonoyl Taurine
产品描述:
Several different arachidonoyl amino acid conjugates, including N-arachidonoyl dopamine and N-arachidonoyl-L-serine, have been isolated and characterized from bovine brain.{9589} N-Nervonyl taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of brain and spinal cord from wild-type and fatty acid amide hydrolase (FAAH) knockout mice.{13153} The levels of N-nervonyl taurine were elevated ~25 fold in FAAH-/- mice compared to wild-type mice, indicating that FAAH utilizes N-nervonyl taurine as a substrate. However, in vitro experiments with purified FAAH indicate that related N-fatty acyl taurines and ethanolamines of similar chain length are hydrolyzed 2,000-50,000 times more slowly by FAAH compared to oleoyl ethanolamide.{13153} The biological function of the taurine fatty acids class of molecules, as well as their relevance to endocannabinoid signaling, remains to be determined. N-acyl taurines bearing polyunsaturated acyl chains can activate members of the transient receptor potential (TRP) family of calcium channels, including TRPV1 and TRPV4.{16245}
保存温度:
-20
运输温度:
-20
预期分子量:
473.8
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1942003-30-6
分子式:
C26H51NO4S
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