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N-Arachidonoyl-L-Serine

品牌：Cayman

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说明书

折扣/货期

货号：10005455-1 mg	规格：1 mg	目录价：￥280
货号：10005455-10 mg	规格：10 mg	目录价：￥1036
货号：10005455-25 mg	规格：25 mg	目录价：￥2240
货号：10005455-5 mg	规格：5 mg	目录价：￥700

产品详情

产品名称:

N-Arachidonoyl-L-Serine

别名:

ARA-S

产品描述:

Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature.{9213} N-Arachidonoyl-L-serine (ARA-S) is one such recently isolated endocannabinoid with an unusual activity profile. ARA-S does not bind to central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors or vanilloid receptor 1 (VR1). Like cannabidiol, ARA-S (5 mg/kg) antagonizes the hypotensive effects of a 10 mg/kg IV bolus of abnormal cannabidiol (Abn-CBD) in an anesthetized rat blood pressure model.{11984} However, similar to Abn-CBD, ARA-S relaxes isolated rat mesenteric arteries and abdominal aorta as well as increases phosphorylation of Akt and mitogen-activated protein kinase (MAPK) in HUVEC.{14066} The precise mechanisms of action by ARA-S and Abn-DBD in various vascular preparations appears to be different and requires further investigation.

保存温度:

-20

运输温度:

-20

预期分子量:

391.5

产品形式:

A solution in ethanol

有效期:

730

纯度:

≥98%