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Gestrinone

品牌：Cayman

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说明书

折扣/货期

货号：10006488-100 mg	规格：100 mg	目录价：￥询价
货号：10006488-1 g	规格：1 g	目录价：￥询价
货号：10006488-500 mg	规格：500 mg	目录价：￥询价

产品详情

产品名称:

Gestrinone

产品描述:

Endometriosesis is common disease characterized by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone is a synthetic steroid used occasionally to treat endometriosesis.{12994} It acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone (LH) and follicle-stimulating hormone (FSH), thus reducing estrogen synthesis.{12994} It also binds to androgen (AR), progesterone (PR), and estrogen (ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin.{13002} Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively.{12992} These values reflect approximately 5-6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.{12992}

保存温度:

-20

运输温度:

-20

预期分子量:

308.4

产品形式:

A crystalline solid

有效期:

1460

纯度:

≥98%