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COX-2 Monoclonal FITC Antibody (Clone CX229)
品牌：Cayman
货号：160113 规格：1 ea (100 μg) 目录价：￥4928
产品详情
产品名称:
COX-2 Monoclonal FITC Antibody (Clone CX229)
别名:
Cyclooxygenase 2|PGHS-2|Prostaglandin H Synthase 2
产品描述:
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosesynthesis of prostaglandins, thromboxanes, and prostacyclins.{500,501} The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; Item No. 17010), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Item No. 17020). COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosesynthesis of PGs under acute inflammatory conditions.{54420,14766} Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman's COX-2 Monoclonal FITC Antibody (Clone CX229) can be used for flow cytometry (FC), immunocytochemistry (ICC), and immunofluorescence (IF) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 in human and ovine samples.
宿主来源:
Mouse
实验应用:
FC, ICC, IF
同种型:
IgG1
免疫原:
Synthetic peptide from the C-terminal region of human COX-2
克隆号:
CX229
保存温度:
-20
运输温度:
-20
产品形式:
100 μg of FITC-labeled purified monoclonal antibody
有效期:
365
来源:
Animal/Mouse
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