COX-2 (human) Monoclonal Antibody (Clone CX229)-单抗-ELISA_抗体_蛋白_核苷酸

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COX-2 (human) Monoclonal Antibody (Clone CX229)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：160112

规格：1 ea (50 µg)

目录价：￥4410

产品详情

产品名称:

COX-2 (human) Monoclonal Antibody (Clone CX229)

别名:

Cyclooxygenase 2|PGHS-2|Prostaglandin H Synthase 2

产品描述:

Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosesynthesis of prostaglandins, thromboxanes, and prostacyclins.{500,501} The COX component converts arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; Item No. 17010), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Item No. 17020). COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosesynthesis of PGs under acute inflammatory conditions.{54420,14766} Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman's COX-2 (human) Monoclonal Antibody (Clone CX229) can be used for immunohistochemistry (IHC) and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 ~70 kDa from human and ovine samples.

宿主来源:

Mouse

实验应用:

IHC, WB

同种型:

IgG1

免疫原:

Synthetic peptide from the C-terminal region of human protein COX-2

克隆号:

CX229

保存温度:

-20