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    Bim antibody [1C2C8]
    品牌:GeneTex
    货号:GTX84981 规格:100μg 目录价:¥6400
    产品详情
    产品名称:
    Bim antibody [1C2C8]
    别名:
    BCL2 like 11 , BAM , BIM , BOD
    反应种属:
    Human, Mouse
    宿主来源:
    Mouse
    实验应用:
    ELISA, ICC/IF, WB
    同种型:
    IgG1
    免疫原:
    Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
    克隆性:
    Monoclonal
    克隆号:
    1C2C8
    纯化方式:
    Purified by affinity chromatography
    偶联:
    Unconjugated
    产品浓度:
    1 mg/ml (Please refer to the vial label for the specific concentration.)
    阳性对照:
    K-562 Cell Slide(GTX25535) , Bim Recombinant Protein
    保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
    运输温度:
    4°C
    预期分子量:
    22
    产品形式:
    Liquid
    存储溶液:
    PBS, 0.02% Sodium azide.
    产地:
    美国
    功能与背景:
    Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
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