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    COX-1 Monoclonal FITC Antibody (Clone CX111)
    品牌：Cayman
    货号：160111 规格：250 µg 目录价：￥4928
    产品详情
    产品名称:
    COX-1 Monoclonal FITC Antibody (Clone CX111)
    别名:
    Cyclooxygenase 1|PGHS-1|Prostaglandin Endoperoxide Synthase 1|Prostaglandin G/H Synthase 1|Prostaglandin H2 Synthase 1
    产品描述:
    Cyclooxygenase 1 (COX-1) is a bifunctional enzyme that exhibits both COX and peroxidase activities.{500,501} It is composed of an N-terminal signal peptide, an EGF-like domain, a membrane binding domain, a catalytic domain, and a C-terminal tail.{4376} COX-1 is constitutively expressed in the gastrointestinal tract, kidney, spleen, liver, and lung and localizes to the endoplasmic reticulum.{1299,1394} The COX component converts arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) to a hydroperoxyl endoperoxide prostaglandin G2 (PGG2; Item No. 17010) and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Item No. 17020), the precursor of PGs, thromboxanes, and prostacyclins.{500,501} COX-1 is the target of many non-steroidal anti-inflammatory drugs (NSAIDs) and is responsible for the undesirable gastrointestinal and renal side effects, such as ulcer formation and reductions in the glomerular filtration rate, respectively.{5282,4411} Cayman’s COX-1 Monoclonal FITC Antibody (Clone CX111) is composed of an anti-COX-1 monoclonal antibody conjugated to fluorescein isothiocyanate (FITC; Item No. 33264) and can be used for flow cytometry (FC).
    宿主来源:
    Mouse
    实验应用:
    FC
    免疫原:
    Purified ovine COX-1
    克隆号:
    CX111
    保存温度:
    -20
    运输温度:
    -20
    产品形式:
    250 µg of FITC-labeled monoclonal antibody
    有效期:
    365
    来源:
    Animal/Mouse
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