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折扣/货期| 货号：10007851 | 规格：1 mg | 目录价：￥2464 |
产品详情
产品名称:
18-hydroxy-11-deoxy Corticosterone
别名:
18-Hydroxydeoxycorticosterone|18-OH-DOC
产品描述:
18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland.{45039,45040} Its biosesynthesis is regulated by adrenocorticotropic hormone (ACTH; Item No. 24257) as well as angiotensin II (Item No. 17150), which increases 18-OH-DOC production in isolated human adrenal glomerulosa cells.{45039,45041} 18-OH-DOC can be formed via conversion of 11-deoxy corticosterone (DOC; Item No. 22916) in human SK-MEL188 melanoma cells.{45042} 18-OH-DOC is an intermediate in the metabolism of progesterone (Item No. 15876) and can be converted to aldosterone (Item No. 15273) by the capsular portion of rat adrenal glands.{45041,45042} Continuous infusion of 18-OH-DOC (200 μg/rat per day) increases systolic blood pressure in uninephrectomized saline-drinking rats.{45040} Plasma levels of 18-OH-DOC are elevated in a db/db mouse model of type 2 diabetes.{45043}
保存温度:
-20
运输温度:
-20
预期分子量:
346.5
产品形式:
A solid
有效期:
1460
CAS号:
379-68-0
分子式:
C21H30O4
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