(±)-Verapamil hydrochloride-细胞染料及荧光探针-深圳九游会j9网站首页有限公司

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(±)-Verapamil hydrochloride

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-V0007-M100	规格：100 mg	目录价：￥434
货号：CDX-V0007-G001	规格：1 g	目录价：￥896
货号：CDX-V0007-G005	规格：5 g	目录价：￥2660

产品详情

产品名称:

(±)-Verapamil hydrochloride

别名:

Manidon

产品描述:

Verapamil hydrochloride is an alpha-adrenergic receptor (alpha-AR) antagonist and calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr (P-glycoprotein). Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models. Verapamil helps treat diabetes by limiting TXNIP expression.

宿主来源:

Synthetic

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

491.06

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at +4°C.