货号:37444-1 mg | 规格:1 mg | 目录价:¥364 |
货号:37444-10 mg | 规格:10 mg | 目录价:¥2856 |
货号:37444-25 mg | 规格:25 mg | 目录价:¥6258 |
货号:37444-5 mg | 规格:5 mg | 目录价:¥1624 |
产品详情
产品名称:
Tat-AKAP79 (326-336) (trifluoroacetate salt)
别名:
Tat-A-kinase Anchor Protein 79 (326-336)
产品描述:
Tat-AKAP79 (326-336) is a peptide composed of the HIV-1 Tat protein transduction domain linked to an 11-amino acid peptide corresponding to residues 326-336 of A-kinase anchor protein 79 (AKAP79).{66516} It inhibits protein kinase A (PKA) or PKC activation-induced sensitization of transient receptor potential vanilloid 1 (TRPV1) in isolated rat dorsal root ganglion (DRG) neurons when used at a concentration of 200 µM. In vivo, Tat-AKAP79 (326-336) inhibits nocifensive behavior induced by formalin or phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in mice. It also increases the latency to paw withdrawal from a radiant heat stimulus and increases the mechanical threshold force to paw withdrawal in a mouse model of carrageenan-induced inflammatory pain.
保存温度:
-20
运输温度:
-20
预期分子量:
2880.3
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C117H211N49O34S • XCF3COOH
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