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Tat-NTS Peptide (trifluoroacetate salt)
品牌:Cayman
货号:37443-1 mg 规格:1 mg 目录价:¥364
货号:37443-10 mg 规格:10 mg 目录价:¥2856
货号:37443-25 mg 规格:25 mg 目录价:¥6258
货号:37443-5 mg 规格:5 mg 目录价:¥1624
产品详情
产品名称:
Tat-NTS Peptide (trifluoroacetate salt)
别名:
Tat-Nuclear Translocations Signal Peptide
产品描述:
Tat-NTS peptide is a cell-penetrating peptide composed of the HIV-1 Tat protein transduction domain linked to a 10-amino acid peptide corresponding to residues 228-237 of the repeat III domain of annexin A1, which functions as a nuclear translocations signal (NTS).{66518} It blocks the protein-protein interaction between annexin A1 and importin β, preventing nuclear translocations of annexin A1 in primary mouse hippocampal neurons.{66518} Tat-NTS inhibits glucose-oxygen deprivation and reperfusion-induced apoptosis in primary mouse hippocampal neurons. In vivo, Tat-NTS (10 mg/kg) reduces infarct size and neuronal apoptosis, as well as decreases the time to reach the platform in the Morris water maze test in a mouse model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).
保存温度:
-20
运输温度:
-20
预期分子量:
2855.4
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C125H212N54O24 • XCF3COOH
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