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    SARS-CoV/SARS-CoV-2 Spike Glycoprotein RBD Chimeric Monoclonal Antibody (Clone D005)
    品牌:Cayman
    货号:30832-100 µl 规格:100 µl 目录价:¥7920
    货号:30832-50 µl 规格:50 µl 目录价:¥4950
    产品详情
    产品名称:
    SARS-CoV/SARS-CoV-2 Spike Glycoprotein RBD Chimeric Monoclonal Antibody (Clone D005)
    别名:
    SARS-CoV/SARS-CoV-2 Spike Protein|SARS-CoV/SARS-CoV-2 Spike RBD|SARS-CoV/SARS-CoV-2 Spike Receptor Binding Domain|SARS-CoV/SARS-CoV-2 Surface Glycoprotein RBD|SARS-CoV/SARS-CoV-2 Surface Glycoprotein Receptor Binding Domain|Severe Acute Respiratory Syndrome Coronavirus/Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein|Severe Acute Respiratory Syndrome Coronavirus/Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein Receptor Binding Domain
    产品描述:
    Severe acute respiratory syndrome coronavirus (SARS-CoV) spike glycoprotein, also known as the surface glycoprotein, is a viral structural protein encoded by the S gene in SARS-CoV RNA that contains the receptor binding domain (RBD).{53462} SARS-CoV is a member of the Betacoronavirus genus of viruses and has an approximately 79% sequence identity with SARS-CoV-2, the causative agent of COVID-19.{53459,53461} SARS-CoV spike glycoprotein is a transmembrane glycoprotein that assembles into homotrimers on the virus surface and is composed of an N-terminal S1 subunit, which contains the receptor binding domain (RBD), and a C-terminal S2 subunit, which facilitates fusion between viral and host cell membranes.{46767,46768,49561} The 193-amino acid RBD of the SARS-CoV spike protein is a target for neutralizing antibodies.{46768,49525} The SARS-CoV RBD, which spans amino acid residues 318 to 510, is 73% identical to that of SARS-CoV-2 and can bind to human angiotensin-converting enzyme 2 (ACE2), which is the host cell surface receptor for both SARS-CoV and SARS-CoV-2.{46768,46767,49525,49561} SARS-CoV is the causative agent of SARS, a primarily respiratory illness characterized by fever, cough, shortness of breath, and an approximately 10% fatality rate.{53461} Cayman's SARS-CoV/SARS-CoV-2 Spike Glycoprotein RBD Chimeric Monoclonal Antibody (Clone D005) is composed of human IgG1κ constant domains and variable regions from a mouse immunized with purified recombinant SARS-CoV spike glycoprotein RBD. It can be used for ELISA.
    宿主来源:
    Chimeric Monoclonal Antibody
    实验应用:
    ELISA
    同种型:
    IgG1
    免疫原:
    Recombinant C-terminal His-tagged SARS-CoV spike glycoprotein RBD
    克隆号:
    D005
    保存温度:
    -20
    运输温度:
    -20
    产品形式:
    50 or 100 µl of protein A-purified monoclonal antibody
    有效期:
    365
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