货号:100-21-100ug | 规格:100ug | 目录价:¥22138 |
货号:100-21-10ug | 规格:10ug | 目录价:¥2836 |
货号:100-21-1mg | 规格:1mg | 目录价:¥88652 |
货号:100-21-250ug | 规格:250ug | 目录价:¥38710 |
货号:100-21-2ug | 规格:2ug | 目录价:¥1163 |
货号:100-21-500ug | 规格:500ug | 目录价:¥57513 |
货号:100-21-50ug | 规格:50ug | 目录价:¥13268 |
产品详情
产品名称:
Recombinant Human TGF-beta1 (HEK293 derived)
别名:
Transforming Growth Factor-beta1, Differentiation inhibiting factor, Cartilage-inducing factor
产品描述:
The three mammalian isoforms of TGF-beta, TGF-beta1, beta2, and beta3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes, including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes, which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-beta isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. TGF-beta1 is the most abundant isoform secreted by almost every cell type. It was originally identified for its ability to induce phenotypic transformation of fibroblasts, and recently it has been implicated in the formation of skin tumors. Recombinant Human TGF-beta1 derived from HEK293 cells is a 25.0 kDa protein with each subunit containing 112 amino acid residues, linked by a single disulfide bond.
宿主来源:
HEK293 cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
25 kDa
产品形式:
Bulk
产地:
美国
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