货号:100-20D-100ug | 规格:100ug | 目录价:¥22246 |
货号:100-20D-10ug | 规格:10ug | 目录价:¥2850 |
货号:100-20D-1mg | 规格:1mg | 目录价:¥89085 |
货号:100-20D-250ug | 规格:250ug | 目录价:¥38900 |
货号:100-20D-2ug | 规格:2ug | 目录价:¥1169 |
货号:100-20D-500ug | 规格:500ug | 目录价:¥57794 |
产品详情
产品名称:
Recombinant Human VEGF-D
别名:
Vascular Endothelial Growth Factor-D, FIGF
产品描述:
VEGF-D, a member of the VEGF/PDGF family of structurally-related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogenesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surface-associated, non-covalent, disulfide-linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant Human VEGF-D is a 26.2 kDa, non-disulfide linked, homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation, the protein migrates as a 20.0-22.0 kDa band by SDS-PAGE analysis under non-reducing conditions.
宿主来源:
HEK293 cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
26.2 kDa
产品形式:
Bulk
产地:
美国
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