货号:120-44-100ug | 规格:100ug | 目录价:¥12757 |
货号:120-44-1mg | 规格:1mg | 目录价:¥51148 |
货号:120-44-20ug | 规格:20ug | 目录价:¥2836 |
货号:120-44-250ug | 规格:250ug | 目录价:¥22322 |
货号:120-44-500ug | 规格:500ug | 目录价:¥33176 |
货号:120-44-5ug | 规格:5ug | 目录价:¥1163 |
产品详情
产品名称:
Recombinant Human R-Spondin-3
别名:
Roof plate-specific spondin-3, RSPO3, PWTSR, THSD2
产品描述:
The R-Spondin (Rspo) proteins belong to the Rspo family of Wnt modulators. Currently, the family consists of four structurally-related, secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. The Rspo proteins can interact with the Frizzled/LRP6 receptor complex in a manner that causes the stabilization, and resulting accumulation, of the intracellular signaling protein, beta-catenin. This activity effectively activates and increases the subsequent nuclear signaling of beta-catenin. R-Spondin can also bind to the previously discovered G-protein coupled receptors, LGR-4 and LGR-5. Rspo/beta-catenin signaling can act as an inducer of the transformed phenotype, and can also regulate the proliferation and differentiation of certain stem cell populations. Recombinant Human R-Spondin-3 is a 26.9 kDa protein consisting of 240 amino acid residues. Due to glycosylation, R-Spondin-3 migrates at an apparent molecular weight of approximately 37.0 kDa by SDS PAGE analysis under reducing conditions.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
26.9 kDa
产品形式:
Bulk
产地:
美国
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