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    Recombinant Human R-Spondin-2
    品牌:PeproTech
    货号:120-43-100ug 规格:100ug 目录价:¥12757
    货号:120-43-1mg 规格:1mg 目录价:¥51148
    货号:120-43-20ug 规格:20ug 目录价:¥2836
    货号:120-43-250ug 规格:250ug 目录价:¥22322
    货号:120-43-500ug 规格:500ug 目录价:¥33176
    货号:120-43-5ug 规格:5ug 目录价:¥1163
    产品详情
    产品名称:
    Recombinant Human R-Spondin-2
    别名:
    Roof plate-specific spondin-2, RSPO2
    产品描述:
    The R-Spondin (Rspo) proteins belong to the Rspo family of Wnt modulators. Currently, the family consists of four structurally-related, secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. The Rspo proteins can interact with the Frizzled/LRP6 receptor complex in a manner that causes the stabilization, and resulting accumulation, of the intracellular signaling protein, beta-catenin. This activity effectively activates and increases the subsequent nuclear signaling of beta-catenin. R-Spondin can also bind to the previously discovered G-protein coupled receptors, LGR-4 and LGR-5. Rspo/beta-catenin signaling can act as an inducer of the transformed phenotype, and can also regulate the proliferation and differentiation of certain stem cell populations. Recombinant Human R-Spondin-2 is a 24.4 kDa protein consisting of 212 amino acid residues. Due to glycosylation, R-Spondin-2 migrates at an apparent molecular weight of approximately 30.0 kDa by SDS PAGE analysis under reducing conditions.
    宿主来源:
    CHO cells
    推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
    预期分子量:
    24.4 kDa
    产品形式:
    Bulk
    产地:
    美国
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