货号:120-28C-100ug | 规格:100ug | 目录价:¥16350 |
货号:120-28C-1mg | 规格:1mg | 目录价:¥88652 |
货号:120-28C-20ug | 规格:20ug | 目录价:¥2900 |
货号:120-28C-250ug | 规格:250ug | 目录价:¥38710 |
货号:120-28C-500ug | 规格:500ug | 目录价:¥57513 |
货号:120-28C-5ug | 规格:5ug | 目录价:¥1163 |
产品详情
产品名称:
Recombinant Human GDF-15/MIC-1
别名:
Growth/Differentiation Factor-15, MIC-1, Macrophage Inhibitory Cytokine 1, Placental TGFbeta, Prostate Differentiation Factor (PDF), PLAB, NRG-1
产品描述:
GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Recombinant Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 112 amino acid polypeptide chains. The calculated molecular weight of Recombinant Human GDF-15/MIC-1 is 24.6 kDa.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
24.6 kDa
产品形式:
Bulk
产地:
美国
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