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折扣/货期| 货号：120-26-100ug | 规格：100ug | 目录价：￥15090 |
| 货号：120-26-1mg | 规格：1mg | 目录价：￥66806 |
| 货号：120-26-20ug | 规格：20ug | 目录价：￥2910 |
| 货号：120-26-250ug | 规格：250ug | 目录价：￥29185 |
| 货号：120-26-500ug | 规格：500ug | 目录价：￥43351 |
| 货号：120-26-5ug | 规格：5ug | 目录价：￥1169 |
产品详情
产品名称:
Recombinant Human NOV
别名:
Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
产品描述:
NOV is a member of the CCN family of secreted, cysteine-rich regulatory proteins. The full-length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm's tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorigenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell-surface integrins, and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities. Recombinant Human NOV is a 36.2 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules): the IGF binding protein (IGFBP) domain; the von Willebrand Factor C (VWFC) domain; the Thrombospondin type-I (TSP type-1) domain; and a C-terminal cysteine knot-like domain (CTCK).
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
36.2 kDa
产品形式:
Bulk
产地:
美国
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