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折扣/货期| 货号：9001413-100 µg | 规格：100 µg | 目录价：￥3374 |
| 货号：9001413-25 µg | 规格：25 µg | 目录价：￥952 |
| 货号：9001413-50 µg | 规格：50 µg | 目录价：￥1820 |
产品详情
产品名称:
Prostaglandin D2 Ethanolamide-d4
别名:
PGD2-EA-d4|Prostamide D2-d4
产品描述:
Prostaglandin D2 ethanolamide (PGD2-EA)-d4 contains four deuterium atoms. It is intended for use as an internal standard for the quantification of PGD2-EA by GC- or LC-mass spectrometry. PGD2-EA is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase.{11045,22752,22753} The biosesynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase.{12142} PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor.{12144} It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.{22753}. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines.{22752}
保存温度:
-20
运输温度:
-20
预期分子量:
399.6
产品形式:
A solution in ethanol
有效期:
730
纯度:
≥99% deuterated forms (d1-d4)
分子式:
C22H33D4NO5
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