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PAF Receptor (human) Monoclonal Antibody (11A4, Clone 21)
品牌:Cayman
货号:160600 规格:1 ea (100 µg) 目录价:¥4410
产品详情
产品名称:
PAF Receptor (human) Monoclonal Antibody (11A4, Clone 21)
别名:
Platelet-activating Factor Receptor
产品描述:
PAF is a potent phospholipid mediator which exerts diverse biological actions by interaction with a G protein-coupled PAF receptor. The PAF receptor has been cloned from a number of species including human, rat, and guinea pig and is characterized as a 7-transmembrane receptor which induces phosphoinositol turnover through G-protein coupling.{5109,5148,5150,5145,5149} Northern blot analysis reveals that the receptor is expressed in leukocytes, placenta, lung, spleen, small intestine, kidney, liver, and brain.{5150,5145} In leukocyte cell populations the receptor is found on platelets, monocytes, neutrophils, and B-cells, whereas resting T-cells and natural killer cell lines do not express the PAF receptor.{4226} Human monocytes treated with INF-γ have a 2-6 fold increase in PAF receptor expression compared to untreated cells.{4225}
宿主来源:
Mouse
实验应用:
(+) ELISA, FC, and ICC; (−) WB
同种型:
IgG2a
免疫原:
Synthetic peptide from the internal region of human PAF receptor
克隆号:
11A4, Clone 21
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein A-purified monoclonal antibody
有效期:
1095
来源:
Animal/Mouse
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