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NMDA Receptor NR1 Subunit Monoclonal Antibody
品牌：Cayman
货号：10607 规格：1 ea 目录价：￥6736
产品详情
产品名称:
NMDA Receptor NR1 Subunit Monoclonal Antibody
产品描述:
The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to Nmethyl- D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1-subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
宿主来源:
Mouse
实验应用:
IP and WB
免疫原:
fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor
保存温度:
-20
运输温度:
-20
产品形式:
Affinity-purified IgG
有效期:
365
来源:
Animal/Mouse
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