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折扣/货期| 货号：F40207-0.08ML | 规格：0.08 ml | 目录价：￥2673.25 |
| 货号：F40207-0.4ML | 规格：0.4 ml | 目录价：￥5765.55 |
产品详情
产品名称:
LIN28A Antibody
产品描述:
LIN28A is a translational enhancer that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Suppressor of microRNA (miRNA) biogenesis, including that of let-7, miR107, miR-143 and miR-200c. Specifically binds miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in pre-miRNA terminal loop, and recruits ZCCHC11/TUT4 uridylyltransferase. This results in the terminal uridylation of target pre-miRNAs. Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation.[UniProt]
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC, IF, ELISA
同种型:
Mouse IgG1, k
免疫原:
LIN28A recombinant protein was used to produce this monoclonal antibody.
克隆性:
Monoclonal (mouse origin)
纯化方式:
Purified
保存温度:
Aliquot the LIN28A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
存储溶液:
In 1X PBS pH 7.4 with 0.09% sodium azide
产地:
美国
生产商:
NSJ Bio
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