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JMJD2D (human, recombinant)
品牌：Cayman
货号：10335 规格：100 µg 目录价：￥6720
产品详情
产品名称:
JMJD2D (human, recombinant)
别名:
JHDM3D|Jumonji Domain Containing 2D|KDM4D|Lysine-Specific Demethylase 4D
产品描述:
Methylation of lysine residues in core histones plays a critical role in regulating gene expression.{18003} Jumonji domain containing 2D (JMJD2D) catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me 2/3), leading to transcriptional repression and activation, respectively.{18004} Like other JmjC protein hydroxylase family members, JMJD2D is an α-ketoglutarate-dependent Fe (II) oxygenase.{17970} Because of their implication in cancer cell growth, jumonji C domain-containing histone demethylase inhibitors may have the capacity to be anticancer agents.{18003}
保存温度:
-80
运输温度:
-80
产品形式:
A solution in 50 mM HEPES, pH 7.4, with 150 mM sodium chloride and 20% glycerol
有效期:
180
纯度:
≥75% estimated by SDS-PAGE
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