货号:AG-CR1-3568-5001 | 规格:5 x 1 mg | 目录价:¥2640 |
货号:AG-CR1-3568-M001 | 规格:1 mg | 目录价:¥660 |
货号:AG-CR1-3568-M005 | 规格:5 mg | 目录价:¥2160 |
产品详情
产品名称:
JC-1
别名:
5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolylcarbocyanine iodide
产品描述:
The membrane-permeant dual-emission potential-sensitive JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 dye can be used as an indicator of mitochondrial membrane potential in a variety of cell types, including myocytes and neurons, as well as in intact tissues and isolated mitochondria. JC-1 accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (590 nm) in healthy cells. After cell injury, as membrane potential decreases, JC-1 monomers are generated, resulting in a shift to green emission (529 nm). The principal advantage of JC-1 relative to other commonly employed fluorescent probes of mitochondrial membrane potential is that it allows qualitative visualization, considering the shift from orange to green fluorescence emission, and quantitative detection, considering the fluorescence intensity ratio.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
652.2
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
3520-43-2 and 47729-63-5
分子式:
C25H27Cl4IN4
溶解度:
Soluble in DMSO, ethanol, methanol or acetone.
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