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折扣/货期| 货号：10811-100 µg | 规格：100 µg | 目录价：￥5474 |
| 货号：10811-50 µg | 规格：50 µg | 目录价：￥4471 |
产品详情
产品名称:
Interleukin-33 Monoclonal Antibody (Clone IL33026B)
别名:
IL-1F11|IL-33|NF-HEV
产品描述:
Interleukin-33 (IL-33), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL-33 is converted by CASP1 to a 18 kDa protein. IL-33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy and anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
宿主来源:
Mouse
实验应用:
ELISA, IP, and WB
同种型:
IgG1κ
免疫原:
recombinant human IL-33
克隆号:
IL33026B
保存温度:
-20
运输温度:
-20
产品形式:
A 1 mg/ml solution in PBS, pH 7.4
有效期:
180
来源:
Animal/Mouse
上一个:Interleukin-33 Monoclonal Antibody (Clone IL333068A)
下一个:Vaspin (human) Monoclonal Antibody (Clone VP63)
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