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折扣/货期| 货号：AG-40B-0105-C010 | 规格：10 ug | 目录价：￥2280 |
产品详情
产品名称:
IL-36gamma (aa 13-164) (mouse) (rec.) (FLAG)
别名:
Interleukin-36gamma; Interleukin-1 Family Member 9; IL-1F9
产品描述:
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
宿主来源:
E. coli
产品浓度:
0.1mg/ml after reconstitution
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~17kDa
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Induces secretion of IL-6 in BMDCs.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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