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折扣/货期| 货号：F40002-0.08ML | 规格：0.08 ml | 目录价：￥2673.25 |
| 货号：F40002-0.4ML | 规格：0.4 ml | 目录价：￥5765.55 |
产品详情
产品名称:
HLA-B Antibody
产品描述:
HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, ELISA
同种型:
Mouse IgM
免疫原:
A portion of amino acids 62-90 from the human protein was used as the immunogen for this HLA-B antibody.
克隆性:
Monoclonal (mouse origin)
纯化方式:
Purified
保存温度:
Aliquot the HLA-B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
生产商:
NSJ Bio
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