官网链接
折扣/货期| 货号：33943 | 规格：25 mg | 目录价：￥3136 |
产品详情
产品名称:
Histone H1 (bovine)
产品描述:
Histone H1 is a nuclear protein that interacts with linker DNA regions between nucleosomes to provide nucleosome core structure stabilization.{60991,52742} Histone H1 subtypes are comprised of a short N-terminal domain, a central globular domain necessary for DNA interaction, and long C-terminal domain that determines subtype binding properties by its variability.{52742} Histones H1.1-H1.5 are expressed in somatic cells in a replication-dependent manner, and cell-type specificity varies based on histone H1 subtype.{60992} Histone H1 is involved in chromatin organization, gene expression, protection of DNA from digestion by micrococcal nuclease, the DNA damage response, and cell differentiation.{52742,60993} Knockdown of H1-2 and H1-4 decreases proliferation of T47D breast cancer cells, and H1-2 knockdown also induces cell cycle arrest at the G1 phase in the same cells.{52745} Histone H1 is highly post-translationally modified, including phosphorylation, acetylation, citrullination, ubiquitination, and methylation.{60993} Phosphorylation of histone H1 at Thr146 is associated with increasing breast cancer tumor grade.{60994} Cayman’s Histone H1 (bovine) protein can be used as a substrate for enzyme activity assays, as well as for Western blot (WB) applications.
保存温度:
-80
运输温度:
-80
产品形式:
A solution in water (frozen)
有效期:
365
纯度:
≥70% estimated by SDS-PAGE
上一个:MERTK Extracellular Domain (human, recombinant)
下一个:c-Kit/CD117 GNNK− Isoform Extracellular Domain (human, recombinant)
您可能感兴趣的产品
Human SLD5 protein, His tag
货号：GTX69573-pro
Human PSMG3 protein, His tag
货号：GTX68801-pro
Human ARL6 protein, His tag
货号：GTX68797-pro
Human HDHD2 protein, His tag
货号：GTX68796-pro
Human TATDN1 protein, His tag
货号：GTX68792-pro
Human ATG10 protein, His tag
货号：GTX68788-pro
Human DYNLRB1 protein, His tag
货号：GTX68785-pro
Human AMMECR1L protein, His tag
货号：GTX68782-pro
促销活动
相关产品推荐
