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FTY720 Hydrochloride
品牌:Stressmarq
货号:SIH-523-5MG 规格:5 mg 目录价:¥734.4
产品详情
产品名称:
FTY720 Hydrochloride
别名:
2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol,hydrochloride; Fingolimod
产品描述:
S1P receptor ligand
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
343.9
产地:
加拿大
功能与背景:
FTY720 is a potent sphingosine 1-phosphate receptors (S1P) agonist once it is phosphorylated by sphingosine kinase. This causes lymphocytes to be sequestered in lymph nodes, which also makes FTY720 an immune modulating drug for multiple sclerosis. It has been shown to stimulate neuronal gene expression, axonal growth and regeneration (3). And recently FTY720 has also been shown to reduce α-Synuclein pathology in parkinsonian GM2+/- Mice (4).
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
162359-56-0
分子式:
C19H34ClNO2
溶解度:
Soluble to 100 mg/ml in DMSO or to 40 mg/ml in ethanol (warmed)
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