货号:SIH-616-5MG | 规格:5 mg | 目录价:¥1368 |
产品详情
产品名称:
C-Dim 12
别名:
3,3'-[(4-Chlorophenyl)methylene]bis[1H-indole]
产品描述:
Displays neuroprotective activity in a mouse model of progressive neurodegeneration
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
356.9
产地:
加拿大
功能与背景:
C-DIM 12 is a nurr1 activator that inhibits bladder cancer growth (1,2). It also inhibits NF-κB and cytokine expression in microglial cells by stabilizing nuclear corepressor proteins, which reduces binding of p65 to inflammatory gene promoters (3). It displays neuroprotective activity in a mouse Parkinson's disease models (4).
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
178946-89-9
分子式:
C23H17ClN2
溶解度:
May be dissolved in DMSO (35 mg/ml); or ethanol (35 mg/ml)
促销活动