货号:11178 | 规格:50 µg | 目录价:¥5110 |
产品详情
产品名称:
DPY-30 (human recombinant)
别名:
DPY-30-like protein|hDPY-30|SAF19
产品描述:
DPY-30 is a component of the MLL1 methylation complex, which interacts directly with Ash2L.{20265} In C. elegans, DPY-30 is required for dosage compensation in XX individuals, and its deletion or mutation is lethal. For XO individuals, DPY-30 is required for proper growth and development.{20266,20267} DPY-30 is a homodimer in solution, and two monomers interact with one Ash2L monomer.{20268} Addition of DPY-30 to the MLL1, WDR5, RbBP5, and Ash2L complex results in a 2-fold increase in methylation rate, from 300x the MLL1 basal rate to 600x the MLL1 basal rate.{20269}
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris, pH 8.0, 100 mM sodium chloride, and 20% glycerol
有效期:
180
纯度:
≥95%
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