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折扣/货期| 货号：AG-CR1-3724-M010 | 规格：10 mg | 目录价：￥480 |
| 货号：AG-CR1-3724-M050 | 规格：50 mg | 目录价：￥1920 |
| 货号：AG-CR1-3724-M250 | 规格：250 mg | 目录价：￥5400 |
产品详情
产品名称:
Darunavir . ethanolate
别名:
TMC114; TMC41629; UIC-94017; HSDB 7788; Prezista
产品描述:
Darunavir ethanolate is a highly potent HIV protease inhibitor (IC50=3-6nM, depending on laboratory HIV-1 strain), an antiretroviral medication used to treat and prevent HIV/AIDS. The ethanolate formulation has some stability advantages compared to the free base Darunavir (Prod. No. AG-CR1-3712). Darunavir ethanolate is a second generation HIV-1 protease inhibitor that inhibits replication of various laboratory strains and clinical isolates of HIV-1, including those resistant to first generation protease inhibitors. It inhibits cell-free diffusion and cell-to-cell spread of HIV-1 in Jurkat cell populations. Formulations containing darunavir have been used in combination therapy for the treatment of HIV. Shown in a SARS-CoV-2 protease structure model study to potentially bind and inhibit the papain like viral protease (PLVP) of SARS-CoV-2, responsible for COVID-19.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
547.7 . 46.0
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
635728-49-3
分子式:
C27H37N3O7S . C2H5OH
溶解度:
Soluble in DMSO (30mg/ml). Very slightly soluble in water (~0.15mg/ml).
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