货号:CDX-C0698-M100 | 规格:100 mg | 目录价:¥1624 |
货号:CDX-C0698-M500 | 规格:500 mg | 目录价:¥6748 |
货号:CDX-C0698-G001 | 规格:1 g | 目录价:¥11186 |
产品详情
产品名称:
Cabozantinib S-malate
别名:
XL184 malate; BMS907351 malate; N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate
产品描述:
The s-malate salt form of Cabozantinib is very potent orally available inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature, angiogenesis and extensive tumor cell apoptosis.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
635.59
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>99% (HPLC)
CAS号:
1140909-48-3
分子式:
C32H30FN3O10
溶解度:
Soluble in DMSO.
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