COX-2 Monoclonal Antibody (Clone 12C10)-单抗-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳九游会j9网站首页有限公司

首页产品中心单抗

COX-2 Monoclonal Antibody (Clone 12C10)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：20198

规格：50 µg

目录价：￥4410

产品详情

产品名称:

COX-2 Monoclonal Antibody (Clone 12C10)

别名:

Cyclooxygenase-2|PGHS-2|Prostaglandin H Synthase 2

产品描述:

Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosesynthesis of prostaglandins, thromboxanes, and prostacyclins.{500,501} The COX component converts arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; Item No. 17010), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Item No. 17020). COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosesynthesis of PGs under acute inflammatory conditions.{54420,14766} Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman's COX-2 Monoclonal Antibody (Clone 12C10) can be used for ELISA, flow cytometry (FC), immunofluorescence (IF), and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 at 72 kDa from human, mouse, and ovine samples.

宿主来源:

Mouse

实验应用:

ELISA, FC, IF, WB

同种型:

IgG1

免疫原:

Synthetic peptide from the C-terminal region of mouse COX-2

克隆号:

12C10

保存温度:

-20