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Clevudine

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-3736-M005	规格：5 mg	目录价：￥360
货号：AG-CR1-3736-M010	规格：10 mg	目录价：￥540
货号：AG-CR1-3736-M050	规格：50 mg	目录价：￥1080

产品详情

产品名称:

Clevudine

别名:

Levovir; L-FMAU; 2'-Fluoro-5-methyl-beta-L-arabinofuranosyl-uracil

产品描述:

Clevudine is a synthetic pyrimidine nucleoside analog antiviral agent with activity against hepatitis B virus (HBV) and Epstein-Barr virus (EBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase and reverse transcriptase, consequently blocking the viral replication. It also blocks the DNA supply of the virus into the nucleus, reducing the amount of cccDNA by 20-100 times. Potentially useful for the treatment of the SARS-CoV-2 (COVID-19) infection, acting as a potent inhibitor of the RdRp protein.

保存温度:

-20°C

运输温度:

Ambient

预期分子量:

260.2

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at -20°C.

产地:

瑞士