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Calcineurin B (human, recombinant)
品牌:Cayman
货号:34631 规格:100 µg 目录价:¥6894
产品详情
产品名称:
Calcineurin B (human, recombinant)
别名:
Calcineurin Subunit B Type 1|CALNB1|CNA2|CNB|CNB1|PPP3R1|Protein Phosphatase 2B Regulatory Subunit 1|Protein Phosphatase 3 Regulatory Subunit B α Isoform 1
产品描述:
Calcineurin B is the regulatory subunit of calcineurin, a serine/threonine phosphatase with roles in T cell activation, cardiac function, learning and memory, apoptosis, and cell cycle regulation.{61745,61746} It is encoded by two genes in mammals, PPP3R1, which is expressed in all tissues except the testes, and the testicular-restricted isoform PP3R2.{61745,61747} Calcineurin B is a calcium-binding protein that contains four EF-hand calcium-binding sites, and calcium binding to calcineurin B is essential to both the phosphatase activity of calcineurin A and binding of inhibitor complexes to calcineurin.{61748,61749} Cayman's Calcineurin B (human, recombinant) protein can be used for binding assays. This protein consists of 187 amino acids and has a calculated molecular weight of 21.4 kDa.
保存温度:
-80
运输温度:
-80
产品形式:
Lyophilized from sterile 50 mM Tris, pH 8.0, with 100 mM sodium chloride, 2 mM DTT and 10% glycerol
有效期:
365
纯度:
≥87% estimated by SDS-PAGE
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