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折扣/货期| 货号：CDX-B0212-G010 | 规格：10 g | 目录价：￥798 |
| 货号：CDX-B0212-G025 | 规格：25 g | 目录价：￥1596 |
| 货号：CDX-B0212-G050 | 规格：50 g | 目录价：￥2660 |
产品详情
产品名称:
Berberine chloride
别名:
Natural Yellow 18; Berberinium chloride; BBR; Umbellatine; Majarine; Thalsine
产品描述:
Natural fluorescent dye, used in histology for staining heparin in mast cells. An isoquinoline alkaloid, which shows antibacterial, antifungal, anti-inflammatory, anti-oxidant, antidiabetic, antiviral and anticancer activity. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. Broad spectrum enzyme inhibitor, affects N-acetyltransferase, cyclooxygenase-2, and topoisomerase activities and gene/protein expression. Increases adiponectin expression, upregulates LDLR and insulin receptor. Anti-hyperglycemic, by inhibition of aldose reductase, inducing glycolysis, preventing insulin resistance through increasing insulin receptor expression and acting like incretins. Activates AMPK and ERK. Potent, uncompetitive, reversible IDO1 inhibitor with IC50 values of 7 µM (cell-based assay) and 9.3 µM (enzymatic assay), and Ki value 8µM. Inhibits BAFF production in H. pylori-induced chronic gastritis.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
335.3 . 36.5
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (TLC)
CAS号:
633-65-8
分子式:
C20H17NO4 . HCl
溶解度:
Soluble in DMSO or methanol. Slightly soluble in ethanol or water.
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