九游会j9网站首页,j9九游会首页登录,j9九游会ag真人官网

深圳九游会j9网站首页有限公司 a1

ATG5 Monoclonal Antibody (Clone 1F8)
品牌：Cayman
货号：28812 规格：100 µg 目录价：￥4690
产品详情
产品名称:
ATG5 Monoclonal Antibody (Clone 1F8)
别名:
APG5-like|Apoptosis-specific Protein|Autophagy Protein 5|Autophagy-related 5|hAPG5
产品描述:
Autophagy-related 5 (ATG5), formerly known as apoptosis-specific protein (ASP), is a protein that is essential to autophagosome elongation.{47096,47097,47098} ATG5 is covalently conjugated to the C-terminal glycine residue of ATG12 (ATG12-ATG5) and forms a non-covalent complex with ATG16 (ATG12-ATG5-ATG16), which functions as an E3 ubiquitin ligase-like enzyme to facilitate LC3 transfer from ATG3 to phosphatidylethanolamine in canonical autophagy. ATG12-ATG5 also binds to the ATG12-ATG5-interaction region of the lysosomally localized protein TECPR1, freeing the TECPR1 pleckstrin homology domain to interact with phosphatidylinositol 3-phosphate components in the autophagosome membrane, promoting autophagosome-lysosome fusion.{47098} Polymorphisms in ATG5 have been associated with various autoimmune diseases, including lupus nephritis and Behçet's disease, gastrointestinal and colorectal cancers, as well as sporadic Parkinson's disease and childhood asthma. Cayman’s ATG5 Monoclonal Antibody (Clone 1F8) can be used for ELISA and immunofluorescence applications.
宿主来源:
Mouse
实验应用:
ELISA and IF
同种型:
IgG1
免疫原:
Full-length human recombinant ATG5 protein
克隆号:
1F8
保存温度:
-20
运输温度:
-20
产品形式:
100 µg Protein G-purified monoclonal antibody
有效期:
1095
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
九游会j9网站首页