货号:AG-20A-0034-C050 | 规格:50 ug | 目录价:¥2760 |
货号:AG-20A-0034-C100 | 规格:100 ug | 目录价:¥4680 |
产品详情
产品名称:
anti-Nampt (Visfatin/PBEF), mAb (OMNI379)
别名:
Pre-B Cell Colony Enhancing Factor 1; PBEF1; Nicotinamide Phosphoribosyltransferase
产品描述:
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosesynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosesynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
实验应用:
ELISA, FACS, ICC, IHC, IP, WB
靶标/特异性:
Recognizes human, mouse and rat Nampt.
同种型:
Mouse IgG2akappa
免疫原:
Recombinant human Nampt (visfatin/PBEF).
克隆号:
OMNI379
产品浓度:
1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
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