anti-ACE2 (human), mAb (AC18F) (ATTO 488)-单抗-ELISA_抗体_蛋白_核苷酸

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anti-ACE2 (human), mAb (AC18F) (ATTO 488)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20A-0032TD-T100

规格：100 tests

目录价：￥4920

产品详情

产品名称:

anti-ACE2 (human), mAb (AC18F) (ATTO 488)

别名:

SARS Receptor; Angiotensin-converting Enzyme 2; ACEH; Metalloprotease MPROT15; SARS-CoV-2 Receptor

产品描述:

Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE, and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung, gut, heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus, 2019-nCoV/SARS-CoV-2, which is cause for pneumonia COVID-19.

实验应用:

FACS

靶标/特异性:

Recognizes human ACE2. Does not detect recombinant human ACE2 that has a tag at the C-terminus of the protein.

同种型:

Mouse IgG1kappa

免疫原:

Recombinant human ACE2.

克隆号:

AC18F

偶联:

ATTO 488